One in six adults and 30-40% of primary care patients suffer from medically unexplained symptoms, chronic functional syndromes or psychosocial factors linked to chronic pain. Collectively these are known as Psychophysiologic Disorders.

Pain is usually misunderstood, both in terms of what causes it and why. This misunderstanding has led to hundreds of millions of chronic pain patients being misdiagnosed and thus receiving treatment that tries to manage the symptom while completely ignoring the cause. To fix this, you first need to understand what pain really is.

Pain is a Danger Signal

 
Psychophysiologic Disorders
 

ALL PAIN IS REAL and all pain is generated in the brain. In fact, the brain is responsible for generating every sensation we feel and, through the nervous system, it controls ALL of our bodily functions. The brain does this by interpreting electrical signals from our body and decides almost instantaneously how to respond; consciously and unconsciously.

Pain and other uncomfortable sensations are how our brain alerts us when it perceives a threat. The threat can be real or imagined, physical or psychological. When the brain’s danger alarm mechanism gets activated, our sympathetic nervous system prepares us for “fight or flight.” When danger signals disappear and/or safety signals are perceived, our parasympathetic nervous system activates so we can “rest and digest.”

When the danger alarm mechanism is being activated longer than it should or in response to benign stimuli, chronic pain and other symptoms can be generated by the brain. This is what we call a Psychophysiologic Disorder.

What are Psychophysiologic Disorders?

 
Psychophysiologic Disorders
 

The term Psychophysiologic Disorders (PPD) is a blend of Psychology (the processes in the mind) and Physiology (the processes in the body). PPDs are pain or illness that develop in response to stress, trauma and other psychological factors including those linked to Adverse Childhood Experiences (ACEs). These symptoms can affect almost any structure, organ system or region in the body. For example, chronic pain, migraine, fibromyalgia, irritable bowel syndrome, chronic fatigue, long Covid, bladder spasm, and pelvic pain are just a few of the conditions to which PPD can contribute.

The good news is that many recent published studies have confirmed that several versions of Pain Relief Psychology can provide far better relief of PPD than the techniques of the past. With this evidence-based approach to diagnosis and treatment, there is every chance that you can achieve relief from your chronic pain or illness.


Watch These Videos

PPDA Co-Founder Dr. Howard Schubiner created these helpful videos with Dr. Sohrab Gollogly. Understanding PPD is a key step in relieving symptoms, so we recommend watching these videos in order.

#1 What is Pain?

 
 

#2 The Brain creates pain

 
 

#3 Predictive Coding

 
 

#4 How to determine the cause of chronic pain

 
 

Common Psychophysiologic Disorders

As suggested by several of the questions above, the more symptoms you have, the more places in your body they’re located, and the more variable they are in severity over time, then the more likely it is that Psychophysiologic (Mindbody) Disorders are a contributing factor. Conditions that commonly (but not always) have a significant contribution from PPD include (but are not limited to) the following (there is more information if you click a diagnosis in blue):

Chronic pain symptoms

Fibromyalgia
Tension headaches
Back, Lumbar or Sciatic Pain
Neck pain
Whiplash
Knee pain
Patellofemoral syndrome
Temporomandibular joint (TMJ) syndrome
Chronic abdominal and pelvic pain syndromes
Chronic tendonitis (in any joint)
Vulvodynia
Piriformis syndrome
Repetitive strain injury
Foot pain syndromes
Myofascial pain syndrome
Amplified Musculoskeletal Pain Syndrome (AMPS)

Autonomic nervous system disorders

Irritable bowel syndrome
Interstitial cystitis (Irritable bladder syndrome)
Postural orthostatic tachycardia syndrome (POTS)
Inappropriate sinus tachycardia
Reflex sympathetic dystrophy (Complex regional pain syndrome)

other Physical symptoms

Headache or Migraine
Insomnia
Some patients with Chronic Fatigue Syndrome (CFS), (aka myalgic encephalitis or systemic exertion intolerance disease*)
Paresthesias (numbness, tingling, burning)
Tinnitus (ringing in the ears)
Dizziness
Eczema
Pseudoseizures
Trigeminal Neuralgia
Globus sensation
Burning chest pain (resembles acid reflux)
Difficulty breathing
Chronic cough
Spastic dysphonia
Chronic hives
Hypersensitivity syndromes (to touch, sound, smells, foods, medications)
Restless Leg Syndrome
Symptoms linked to nerve dysfunction such as dizziness, ringing in the ears (tinnitus), visual disturbances, pseudoseizures and numbness or tingling in the arms or legs

* Systemic exertion intolerance disease has been identified by the Institutes of Medicine as an organic disorder. There remains controversy about this disorder and its relation to chronic fatigue syndrome (CFS)

 

Psychological Symptoms

Anxiety
Depression
Obsessive-compulsive disorder
Post-traumatic stress disorder (PTSD)
Eating disorders
Substance use disorders

Disclaimer

 

PPD does NOT include

Cancers
Rheumatoid conditions
Infections (such as COVID-19*)
* The cause of “Long-Haul” COVID-19 is undergoing intensive study, but there are many patients who have recovered or improved with PPD treatment techniques and increasing evidence that psychological factors can be involved.

ask your doctor

Since structural damage or organ disease processes can also cause the symptoms on this list, it is important to first rule out serious medical conditions with your doctor. Ask your doctor if it’s safe for you to pursue emotional therapy-based treatment for your symptoms.

 

There is hope!

Despite the discomfort and serious nature of these symptoms, PPD does not damage your organ tissue or body structure and you no longer have to settle for just managing your chronic pain or other symptoms. Psychophysiologic Disorders are BENIGN and CURABLE!

  1. Learn more about PPD - an important first step toward recovery

  2. Use our resources to begin your recovery from home

  3. Find a PPD practitioner near you to get diagnosed and/or treated

Your road to recovery begins now! Learn more by clicking a button below.